Some of the most puzzling pieces of history are tantalizing works from the distant past which seems to have no explanation.
The staff at a library in Ohio are baffled by a bizarre mystery surrounding a bevy of empty steak sauce bottles that have been found hidden throughout the building.
A former molecular biologist who has been studying crop circles for the last 20 years believes that the enigmatic formations contain coded messages and that he has deciphered them.
An attempt to locate the remains of the final 'official' victim of infamous serial killer Jack the Ripper has spawned a new mystery of sorts.
Researchers are baffled by bizarre behavior exhibited by humpback whales where the normally solitary creatures have been spotted appearing in clusters numbering in the hundreds.
Almost an eerie doppelganger to unexplained vanishings are baffling cases of people whose identities were a mystery.
While television may make it seem like it takes only an hour to solve a medical mystery, there are some puzzling conditions which remain 'to be continued.'
By their very nature, most mysteries are already rather creepy, but there are some cases that are stand out as particularly unnerving.
A strange controversy has erupted in a small Spanish town after a 'ghost child' was allegedly photographed at the town hall, leading residents to call for an exorcism, but the mayor refuses to do it.
An ambitious historian hopes to get to the bottom of a legendary tale which has mystified paranormal researchers for decades.
A fresh look at one of the ocean's most vexing sea creatures, the cockeyed squid, may have finally solved the mystery of the animal's bizarre appearance.
Unlike many mystery sound cases which seem to rely only on witness recollection, a recent event in the UK was recorded by a man who managed to capture the noise using his cell phone.
A night vision camera in an Australian forest captured a puzzling glimpse of a diminutive creature that no one seems to be able to identify.
NASA has commissioned a new study that may potentially solve the longstanding marine mystery of why some sea creatures become beached.
The story of the North Dakota tracker who claimed to have followed a seven-mile-long trail of Bigfoot prints has taken an odd turn via an anonymous letter sent to a local TV station.
Residents of the Mexican state of Michoacan were baffled by the appearance of a bizarre cylindrical cloud that seemed to sport a glowing center.
Egyptologist John Anthony West is fighting cancer, and a Fundly campaign has been set up to help with the costs.
Australia's Thylacine Awareness Group have released a new image which features a mysterious canine-looking creature that may be the legendary Tasmanian Tiger.
George Knapp shares a number of news items that have recently caught his attention.
Newly published research by Russian geologists raises new questions about the infamous Tunguska blast and seems to upend one longstanding theory about the mysterious event.
The Canadian army has dispatched a pair of acoustic specialists to a region of the country that has been purportedly plagued by a mysterious sound for months.
Researchers at Princeton University believe they may have finally solved the mystery of Namibia's perplexing 'fairy circles.'
A multinational team devoted to finding the infamous lost airliner MH370 have officially suspended their underwater search for the vanished plane and its unfortunate passengers.
Over the course of every year, it seems, news emerges that promises to finally put to rest some longstanding mystery that has stumped us for ages only to fall short once again and 2016 was no different.
A town in Maryland plagued by the infamous mystery boom phenomenon hopes that a new study may finally find a source for the maddening sounds.
In tandem with his appearance on tonight's program, David Paulides shares this incredible look at the early stages of a forthcoming documentary about the infamous Missing 411 phenomenon.
Made famous through the research of frequent C2C guest David Paulides, the phenomenon of people mysteriously vanishing from National Parks has captivated paranormal enthusiasts over the last few years.
In an interview with China's first astronaut, the pioneering explorer revealed a remarkable experience he had during his historic trip to space.
A search by the Royal Canadian Navy has determined that an anomalous object discovered by a diver off the coast of British Columbia earlier this month is not an infamous atomic bomb which went missing in 1950.