In a night of special Open Lines, Art invited callers to share their thoughts on how the world would come to an end. One repeated assertion was that it would be "by man's hand," either through nuclear exchanges or biowarfare.

A female caller referenced the T.S. Eliot line "not a bang, but a whimper," in her prediction that the male Y chromosome would die out, and then the surviving women would kill each other off in two generations "out of boredom." Another caller foresaw a "series of jabs," that would include famine, extreme weather, earthquakes, and plagues followed by a pole shift that would "kill everyone that wasn't already dead."

After a long hiatus, the notorious phone caller known as J.C. returned to subject Art to one of his trademark harangues. "I'm God's General in the war against porn," he declared, suggesting that the "atrocities in Iraq" were caused by the porn industry.